Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias
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چکیده
Citation for published version: Stoeck, K, Sanchez-Juan, P, Gawinecka, J, Green, A, Ladogana, A, Pocchiari, M, Sanchez-Valle, R, Mitrova, E, Sklaviadis, T, Kulczycki, J, Slivarichova, D, Saiz, A, Calero, M, Knight, R, Aguzzi, A, Laplanche, J-L, Peoc'h, K, Schelzke, G, Karch, A, van Duijn, CM & Zerr, I 2012, 'Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias: a longitudinal multicentre study over 10 years' Brain, vol 135, no. 10, pp. 3051-3061., 10.1093/brain/aws238
منابع مشابه
Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt–Jakob disease and rapid dementias: a longitudinal multicentre study over 10 years
To date, cerebrospinal fluid analysis, particularly protein 14-3-3 testing, presents an important approach in the identification of Creutzfeldt-Jakob disease cases. However, one special point of criticism of 14-3-3 testing is the specificity in the differential diagnosis of rapid dementia. The constant observation of increased cerebrospinal fluid referrals in the national surveillance centres o...
متن کاملOp-brai120155 3051..3061
Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt–Jakob disease and rapid dementias: a longitudinal multicentre study over 10 years Katharina Stoeck, Pascual Sanchez-Juan, Joanna Gawinecka, Alison Green, Anna Ladogana, Maurizio Pocchiari, Raquel Sanchez-Valle, Eva Mitrova, Theodor Sklaviadis, Jerzy Kulczycki, Dana Slivarichova, Albert Saiz, Miguel Calero, Richard Knight, Adriano ...
متن کاملCSF lactate dehydrogenase activity in patients with Creutzfeldt-Jakob disease exceeds that in other dementias.
The diagnosis of Creutzfeldt-Jakob disease (CJD) is still made by exclusion of other dementias. We now evaluated lactate dehydrogenase (LDH) in the cerebrospinal fluid (CSF) as a possible additional diagnostic tool. CSF LDH levels of patients with CJD (n = 26) were compared with those in other dementias (n = 28). LDH isoenzymes were determined in a subset (n = 9). Total LDH and isoenzyme LDH-1 ...
متن کاملCreutzfeldt-Jakob disease: A case report
Background: Creutzfeldt-Jakob disease (CJD) as a life-threatening neurodegenerative disorder is not usually diagnosed in early stages of the disease because of a variety in its clinical manifestations. This study aimed to present a middle-aged woman with psychiatric symptoms who ultimately was diagnosed as a CJD case. Case presentation: This 48-year-old woman had progressive symptoms of depres...
متن کاملApplicability of long-term electroencephalography in pre-mortem diagnosis of Creutzfeldt–Jakob disease: A case report
Creutzfeldt-Jakob disease accounts for more than 90% of all sporadic prion disease cases. The molecular MM2 genotype has been divided into cortical and thalamic subtypes based on structures involved and is characterized clinically by progressive dementia without ataxia or typical electroencephalography changes. Proposed diagnostic criteria for MM2 cortical type sporadic Creutzfeldt-Jakob diseas...
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تاریخ انتشار 2016